de toekomstperspectieven geschetst als op de Journées internationales de la So- ciété Française de Neurologie 2013 (24): nieuwe researchcriteria met inclusie van biomarkers in het CSV, en structurele, metabole en amyloïdscanning, waarmee de diagnose van ziekte van Alzheimer in een prodromaal stadium kan worden gesteld, voor ze enige weerslag heeft op de autonomie. De therapeutische studies bij de ziekte van Alzheimer hebben over het algemeen negatieve uitkomsten ge- geven. Alle hoop wordt nu gesteld in de studies die lopen bij patiënten met de ziekte van Alzheimer in een prodromaal en dus een vroeg stadium, ook al is het methodologisch erg complex om derge- lijke studies uit te voeren. het volgende congres van de WCN, hoofdstad Santiago. 1. mental deterioration in the elderly. Lancet 1974;2:207-9. Learning. Oxford University Press, Londres, 1961. Paris, 2006. Brain Stimulation in advanced Parkinson disease. Ann Neurol. 2013;74(3):449-57. independent and location-linked representations of sound objects. Neuroimage 2013;73:40-9. evidence from neuroimaging and neurostimulation. Neuropsychol Rehabil 2011;21(5):742-54. training and brain stimulation in chronic aphasia. Neuropsychol Rehabilitation;21(5):717-41. of circuit training as alternative to usual physiotherapy after stroke: randomized controlled trial. BMJ 2012;344:e2672. DaTscan SPECT imaging on clinical management, diagnosis, confidence of diagnosis, quality of live, health resource use and safety in patients with clinically uncertain parkinsonian syndromes: a prospective 1-year follow-up of an open-label controlled study. Journal of neurology neurosurgery and psychiatry 2012;83:620-8. diagnosis of dementia due to Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer disease. Alzheimer's Dement 2011;7(3):263-9. criteria for the diagnosis of Alzheimer's disease: revising the NINCDS-ADRDA criteria. The lancet Neurology 2007;6(8):734-46. defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement 2011;7(3):280-92. Alzheimer-related changes. Acta Neuropathol 1991;82:239-59. validation of a cued recall memory deficit in prodromal Alzheimer disease. Neurology 2012;78(6):379-86. biomarkers and incipient Alzheimer disease in patients with mild cognitive impairment. JAMA, 2009;302(4):385-93. 18F-flutemetamol amyloid imaging in Alzheimer disease and mild cognitive impairment: a phase 2 trial. Ann Neurol 2010; 68(3):319-29. AV-45) PET to assess amyloid burden in Alzheimer's disease dementia, mild cognitive impairment and normal aging. Alzheimers Dement 2013;9(0):S72-S83. al. The Challenges of Tau Imaging. Future Neurology 2012; 7(4):409-421. selective and specific PET tracer for imaging of tau pathologies. J Alzheimers Dis. 2012 ;31(3):601-12. challenge. Funct Neurol 2013;28(3):167-73. Assessment of system dysfunction in the brain through MRI-based connectomics. Lancet Neurol 2013;12(12):1189-99. thrombectomy after failure of intravenous thrombolysis in acute ischemic stroke: preliminary results of a multicenter prospective observational study. Poster 361/Session 2; WCN 2013, Vienne. met anti-NMDA-receptorantilichaam positieve encephalitis op basis van een matuur teratoom in het mediastinum. Neurone 2013;18(9):47-51. nouveaux concepts, nouveaux enjeux. Revue Neurologique 2013;169(10):677-833. |